Something rotten is brewing beneath the industrial mecca known as Raccoon City. Unknown to its millions of residents, a huge underground bioengineering facility known as The Hive has accidentally unleashed the deadly and mutating T-virus, killing all of its employees.
To contain the leak, the governing supercomputer, Red Queen, has sealed all entrances and exits. Now a team of highly-trained super commandos including Rain (Michelle Rodriguez – The Fast and the Furious, Girlfight), Alice (Milla Jovovich – The Fifth Element) and Matt (Eric Mabius – Cruel Intentions) must race to penetrate The Hive in order to isolate the T-virus before it overwhelms humanity.
To do so, they must get past the Red Queen’s deadly defenses, face the flesh-eating undead employees, fight killer mutant dogs and battle The Licker, a genetically mutated savage beast whose strength increases with each of its slain victims.